Celentyx: Assessing immunomodulator impact on human Th17 cells (download pdf)

Celentyx: Assessing immunomodulator impact on clinical samples (download pdf)

Enhancing the anti-lymphoma potential of 3,4-methylenedioxymethamphetamine (‘ecstasy’) through iterative chemical redesign: mechanisms and pathways to cell death
Wasik AM, Gandy MN, McIldowie M, Holder MJ, Chamba A, Challa A, Lewis KD, Young SP, Scheel-Toellner D, Dyer MJ, Barnes NM, Piggott MJ, Gordon J. (2011) Investigational New Drugs (download pdf)

Of Mice and Men: the potential of high-resolution human immune cell assays to aid the pre-clinical to clinical transition of drug development projects
Brady CA. (2009) Drug Discovery World Winter 2008/2009 (download pdf)

Harnessing serotonergic and dopaminergic pathways for lymphoma therapy: Evidence and aspirations
Barnes NM and Gordon J. (2008) Seminars in Cancer Biology 18:218-225 (download pdf)

Teaching Old Drugs New Tricks
Brady CA, Boyd A, Gordon J, Barnes NM. (2007) European Pharmaceutical Contractor Autumn 2007:100-104 (download pdf)

Tone sets the signaling pathways and transcriptome generated in model CD40-pluricompetent L3055 Burkitt's lymphoma cells
Stewart R, Wei W, Challa A, Armitage RJ, Arrand JR, Rowe M, Young LS, Eliopoulos A and Gordon J. (2007) Journal of Immunology 179:2705-2712
(download pdf)

Dopamine targets cycling B cells independent of receptors transporter for oxidative attack: Implications for non-Hodgkin’s lymphoma
Meredith EJ, Holder MJ, Rosén A, Drake-Lee A, Dyer MJ, Barnes NM and Gordon J. (2006) PNAS 103:13485-13490 (download pdf)

Differential survival of leukocyte subsets mediated by synovial, bone marrow, and skin fibroblasts: site-specific versus activation-dependent survival of T cells and neutrophils
Filer A, Parsonage G, Smith E, Osborne C, Thomas AM, Curnow SJ, Rainger GE, Raza K, Nash GB, Lord J, Salmon M, Buckley CD (2006) Arthritis Rheum. 54:2096-2108. (download pdf)

Close encounters of the monoamine kind: immune cells betray their nervous disposition
Meredith EJ, Chamba A, Holder MJ, Barnes NM and Gordon J. (2005) Immunology 115:289-295 (download pdf)

The serotonin transporter (SLC6A4) is present in B-cell clones of diverse malignant origin: probing a potential anti-tumor target for psychotropics
Meredith EJ, Holder MJ, Chamba A, Challa A, Drake-Lee A, Bunce CM, Drayson MT, Pilkington G, Blakely RD, Dyer MJ, Barnes NM and Gordon J. (2005) Faseb J. 19:1187-1189 (download pdf)

Inhibition of T cell apoptosis in the aqueous humor of patients with uveitis by IL-6/soluble IL-6 receptor trans-signaling
Curnow SJ, Scheel-Toellner D, Jenkinson W, Raza K, Durrani OM, Faint JM, Rauz S, Wloka K, Pilling D, Rose-John S, Buckley CD, Murray PI, Salmon M. (2004) J. Immunol 173:5290-5297 (download pdf)

Lymphocytes transport serotonin and dopamine: agony or ecstasy?
Gordon J and Barnes NM. (2003) Trends in Immunology 24:438-443 (download pdf)

Selective serotonin reuptake inhibitors directly signal for apoptosis in biopsy-like Burkitt lymphoma cells
Serafeim A, Holder MJ, Grafton G, Chamba A, Drayson MT, Luong QT, Bunce CM, Gregory CD, Barnes NM, Gordon J. (2003) Blood 101:3212-3219 (download pdf)

Modelling the human immune response: can mice be trusted? Commentary
Gordon J, Grafton G, Wood P, Larché M, Armitage R. (2001) Current Opinion in Pharmacology 1:431–435 (download pdf)

A review of central 5-HT receptors and their function
Barnes NM and Sharp T. (1999) Neuropharmacology 38:1083-1152 (download pdf)

The interplay between T helper subset cytokines and IL-12 in directing human B lymphocyte differentiation
Gagro A and Gordon J. (1999) European Journal of Immunology 29:3369-3379 (download pdf)

Immunoglobulin isotype production by cycling human B lymphocytes in response to recombinant cytokines and anti-IgM
Flores-Romo L, Millsum MJ, Gillis S, Stubbs P, Sykes C, Gordon J. (1990) Immunology 69:342-347

Mechanisms of tumour cell escape encountered in treating lymphocytic leukaemia with anti-idiotypic antibody
Gordon J, Abdul-Ahad AK, Hamblin TJ, Stevenson FK, Stevenson GT. (1984) Br J Cancer. 49(5):547-57.

Preliminary experience in treating lymphocytic leukaemia with antibody to immunoglobulin idiotypes on the cell surfaces
Hamblin TJ, Abdul-Ahad AK, Gordon J, Stevenson FK, Stevenson GT. (1980) Br J Cancer 42(4):495-502.