Home > Immunology Assays > T Cell Activation Assays
Assays for measuring T cell activation, killing, proliferation, signalling and synapse formationCelentyx can run high-throughput plate-based and high-content assays of T cell activation (including on purified T cell subsets) using a number of different readouts and performed on human primary cells either from healthy volunteers or patients with underlying disease:
Assays may be suitable for evaluating modulators of BiTEs, CD3, CD27, CD28, CD40, CD40L, CD70, CD80, CD86, CTLA-4, JAK1, JAK2, JAK3, ICOS, ICOSL, IL-2R, IL-9R, IL-21R, OX40, OX40L, PD-1, PDL-1, TIGIT, TIM-3, STAT1, STAT3, STAT5 and others.
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